|
Determination of Acrylonitrile in Cosmetics by GC-MS Method |
|
View Full Text Download reader |
DOI:10.3969/j.issn.1004-4957.年份.月份 |
KeyWord:cosmetics acrylonitrile solid phase extraction gas chromatography-mass spectrometry |
Author | Institution |
LIU Xi,MA Qiang,XI Haiwei,WANG Ye,BAI Hua,WANG Chao |
中国检验检疫科学研究院 |
|
Hits: 2687 |
Download times: 1526 |
Abstract: |
A gas chromatography-mass spectrometric method was developed for the determination of acrylonitrile in cosmetic samples.The cosmetics were ultrasonically extracted with methanol and then centrifuged.The concentrated supernatant was purified with an Oasis HLB solid phase extraction cartridge using 20% methanol solution as washing agent and 80% methanol solution as eluting agent.The eluent was further dehydrated with anhydrous sodium sulphate.The analysis was carried out with a capillary column(HP INNOWax 60 m×025 mm×050 μm) under electron ionization conditions at a flow rate of 12 mL/min.The quantitation was performed by the external standard method under selected ion monitoring(SIM) mode using monitering ions of m/z 53,52 and 26.The recoveries were in the range of 84%-101% with relative standard deviations(RSDs) of 11%-42%.The detection limit was 04 mg/kg.This method was proved to be simple,accurate,and was suitable for the determination of acrylonitrile in cosmetics. |
Close |