Determination of Thirteen Plasticizers in Food Plastic Packaging Materials by Capillary Column Gas Chromatography

KeyWord:gas chromatography  plasticizer  Soxhlet extraction technique  solid phase extraction

Abstract:

      A capillary column gas chromatographic method was developed for the separation and determination of thirteen plasticizers£¬including dimethyl phthalate acid ester£¨DMP£©£¬diethyl phthalate acid ester£¨DEP£©£¬dipropyl phthalate acid ester£¨DnPP£©£¬diisobutyl phthalate acid ester£¨DIBP£©£¬dibutyl phthalate acid ester£¨DBP£©£¬diamyl phthalate acid ester£¨DAP£©£¬bisphenol A£¨BPA£©£¬di n hexyl phthalate acid ester£¨DHP£©£¬butyl benzyl phthalate acid ester£¨BBP£©£¬di 2 ethylhexyl adipate£¨DEHA£©£¬di£¨2 ethylhexyl£© phthalate acid ester£¨DEHP£©£¬dioctyl phthalate acid ester£¨DOP£© and dinonyl phthalate acid ester£¨DNP£© in plastic packaging materials for foodstuff. The analytes were extracted with hexane from samples by Soxhlet extraction technique£¬then purified by silica solid phase extraction. Three key factors such as rinse solvent£¬eluting solvent and eluting volume were optimized. Hexane and toluene£¨1¡Ã1£¬by volume£© were used as rinse solvents£¬2 mL ethyl acetate was used as eluting solvent. After filtration£¬the eluate was determined by gas chromatography with flame ionization detector£¨GC/FID£©. The calibration curves of thirteen plasticizers were linear in the range of 0ª±1-1 000 mg/L with detection limits of 0ª±005-0ª±030 mg/L. The spiked recoveries ranged from 90% to 116% with relative standard deviations of 2ª±2%-4ª±9%. The method was successfully applied in the determination of plasticizers in plastic packaging materials for foodstuff.