Determination of Pyrethroid Residue in Beef by GC-MS

KeyWord:gas chromatography-negative chemical ionization mass spectrometry  column chromatography  selected ion monitoring  pyrethroid  beef

Abstract:

      A gas chromatography(GC£©-negative chemical ionization-mass spectrometric(NCI/MS£© method was established for the determination of 7 frequently used pyrethroid insecticides residues in beef.The sample was extracted with acetonitriles and cleaned up with neutral alumina chromatographic column,and then determined by GC-MS under the selected ion monitoring mode(SIM£©.Good accuracy,precision and sensitivity were obtained.The calibration curves of 7 pyrethriods were linear between peak areas and concentrations in the range of 10-1 000 ¦Ìg/L with correlation coefficients(r2£© more than 0.997.The recoveries of 7 pyrethriods were in the range of 80%-108% at three spiked concentration levels of 10,20,50 ¦Ìg/kg,with relative standard deviations(RSDs£© less than 12.5%.The limits of detection(LOD£© for all pyrethroid ranged from 0.10 ¦Ìg/kg to 2.5 ¦Ìg/kg and the limits of quantitation(LOQ£© were in the range of 0.50-5.0 ¦Ìg/kg.