|
| Study on Synthesis of Dihydromyricetin-Zinc Complex and Its Interaction with DNA |
| |
| View Full Text Download reader |
| DOI：10.3969/j.issn.1004-4957.年份.月份 |
| KeyWord:dihydromyricetin - zinc complex DNA fluorescence spectrometry viscosity measurements interaction |
| Author | Institution |
| 袁娟，郭清泉，曾金华，舒绪刚 |
1.广东工业大学轻工化工学院;2.仲恺农业工程学院化学化工学院 |
|
| Hits: 2249 |
| Download times: 1131 |
| Abstract: |
| A complex of dihydromyricetin-Zn(DMY-Zn)was prepared firstly，the interaction of DMY-Zn complex with DNA was investigated by using fluorescence titration that ethidium bromide(EB) as a fluorescence probe and viscosity measurements.The results indicated that DMY and Zn2+ ions are easy to form complexes which compositions were tested as ［C15H10O8Zn］?2H2O by characterization using UV-Vis，IR spectroscopy，elemental analysis and thermal gravimetric analysis(TG-DTA).With the strong interaction with DNA，the DMY-Zn complex can compete with the strong intercalator ethidium bromide to intercalate into the stacked base pairs through the intercalation which the Stern-Volmer quenching constant Ksq is equal to 1.01. |
| Close |