|
| Microwave and Ultrasonic-assisted Synthesis of PEI-capped Mn-doped ZnS QDs for Room Temperature Phosphorescence Detection of Guanosine 5’-triphosphate |
| |
| View Full Text Download reader |
| DOI：10.3969/j.issn.1004-4957.年份.月份 |
| KeyWord:Mn-doped ZnS quantum dots microwave and ultrasonic-assisted synthesis room temperature phosphorescence guanosine 5’-triphosphate |
| Author | Institution |
| 任呼博，杨成雄，严秀平 |
南开大学化学学院分析科学研究中心，药物化学生物学国家重点实验室 |
|
| Hits: 4964 |
| Download times: 1461 |
| Abstract: |
| High quality PEI-capped Mn-doped ZnS QDs were prepared via a microwave and ultrasonic-assisted synthesis for room temperature phosphorescence detection of guanosine 5’-triphosphate(GTP).Such QDs showed high selectivity and sensitivity for GTP，and could distinguish GTP from adenosine triphosphate(ATP)，cytidine triphosphate(CTP)，uridine triphosphate(UTP)，adenosine diphosphate(ADP) and adenosine monophosphate(AMP).The room temperature phosphorescence response of the PEI-capped Mn-doped ZnS QDs for GTP reached equilibrium in 3 min.PEI-capped Mn-doped ZnS QDs gave a detection limit(3s) of 0.6 μmol/L for GTP.The developed phosphorescence probe favors biological applications since the interference from scattering light and autofluorescence can be effectively eliminated.The developed method has been successfully applied for the room temperature phosphorescence detection of GTP in cancer cell extract. |
| Close |