The Research of Reference Material Chloramphenicol in Fish

KeyWord:reference material£¨RM£©  certification  property value  uncertainty evaluation  chloramphenicol  fish

Abstract:

      The research of chloramphenicol reference material in carps meat as a matrix was investigated.The reference material was prepared by adding chloramphenicol to feeding carps£¬and the homogeneity and stability of samples were detected by liquid chromatography-tandem mass spectrometry£¨LC-MS/MS£©.A cooperative certification was conducted by 8 laboratories.The property value is 5.23 ¦Ìg/kg £¬and the expanded uncertainty is 0.46 ¦Ìg/kg as the coverage factor is 3.The result showed that the uniformity of samples was good£¬and the expiration date of reference material was at least 18 months.The reference material can be used in the quality control of residues detection.