| A gas chromatography-mass spectrometric method based on deuterium isotope internal standard was developed for the rapid determination of musk xylene(MX) in food flavors.In order to disperse sample matrix into extraction solvent,samples were distributed by use of a vortex mixer,and then extracted for 20 min with an ultrasonic generator.The influences of solvent type,solvent consumption and ultrasonic time on extraction efficiencies of the target compounds were discussed.The analyte was quantitatively analyzed by deuterium isotope internal standard method under selected ion monitoring(SIM) mode.The influences of different polarity chromatographic columns on separation were analyzed,the characteristic ions and their abundances were determined.Under the optimal conditions,the calibration curve of MX was in the range of 0.025-0.5 mg/L with a correlation coefficient of 0.999 6.The average recoveries were in the range of 94%-116% with relative standard deviations of 4.2%-6.5%.The detection limit and quantitation limit of MX were 0.11 mg/kg and 0.38 mg/kg,respectively.The results showed that the method was simple,rapid,sensitive and accurate,and was suitable for the rapid determination of MX in food flavors. |