Simultaneous Determination of 71 Pesticides Residues in Marine Sediments by ASE-SPE/GC-MS/MS

KeyWord:ASE  GC-MS/MS  marine sediments  pesticides

Abstract:

      An accelerated solvent extraction£¨ASE£©/gas chromatography-tandem mass spectrometric£¨ASE/GC-MS/MS£© method combined with solid phase extraction£¨SPE£© was developed for the simultaneous determination of 71 pesticides residues in marine sediments£®The best extraction temperature and static time were 100 ¡æ and 5 min in 1 cycle£¬respectively.Under the conditions£¬the sample was extracted with a mixture of hexane-acetone£¨1¡Ã1£©,cleaned up on a Carbon SPE cartridge and determined by MS/MS under multiple reaction monitoring mode£¨MRM£©.The calibration curves showed good linearities£¨r2£¾0.99£© in the range of 1.0 -500 ¦Ìg?L-1 for all pesticides£¬and the limits of detection£¨LOD,3¦Ò£© ranged from 0.29 ¦Ìg?kg-1 to 108.43 ¦Ìg?kg-1.The recoveries of the pesticides at a spiked level of 100 ¦Ìg?kg-1 were in the range of 51.3%-104.6%with RSDs£¨n=6£© of 0.1%-13.5%.