| Chirality is the intrinsic attribute of the nature.It is of great importance to develop new，rapid,efficient and sensitive chiral separation and analysis methods for enantioselective synthesis,chiral drugs pharmacological research,enantiomeric purity analysis and environmental monitoring.Metal nanoparticles can be used as ideal supporting materials for chiral chromatography due to their large surface area,good stability and easy post-functionalization.Furthermore,some kinds of metal nanoparticles own unique properties for surface plasmon resonance resulting from the collective oscillations of conduction band electrons,fluorescence and catalysis,so the practical applications and theoretical studies of metal nanoparticles in the area of chiral sensors are going deep.In this review,the recent applications of different metal nanoparticles (gold nanoparticles,silver nanoparticles,quantum dots,magnetic nanoparticles,etc.) in chiral separation and recognition are reviewed,and the future developments in this field are also prospected. |