| In this paper，poly（L-glutamic acid ethyl ester） was synthesized.After poly（L-glutamic acid ethyl ester） was dissolved in chloroform，a chiral stationary phase based on the poly（L-glutamic acid ethyl ester） coated onto silica gels was successfully prepared.The chiral stationary phase was used for the separations of 4-racemates(furoin,omeprazole,naproxen,tetramizole-hydrochloride) and 9-isomers(o,m,p-iodoaniline,o,m,p-chloroaniline,o,m,p-bromoaniline,o,m,p-nitroaniline,o,m,p-toluidine,o,m,p-chlorophenol,o,m,p-dinitrobenzene,o,m,p-benzenediol,o,m,p-aminophenol) with HPLC using different ratios of hexane-isopropanol and hexane-ethanol as mobile phases.The experimental results showed that poly（L-glutamic acid ethyl ester） possesses a good ability for separating enantiomers and isomers. |