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Electrochemical Behaviors of Meloxicam at AB and [BnMIM]PF6 Modified Carbon Paste Electrode and Its Electrochemical Determination |
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DOI:10.3969/j.issn.1004-4957.年份.月份 |
KeyWord:meloxicam [BnMIM]PF6 AB modified carbon paste electrode electrochemical behaviors electrochemical determination |
Author | Institution |
FENG Yun,WU Rui,YOU Wei,PENG Juan,GAO Zuo-ning* |
1.宁夏大学化学化工学院;2.银川大学石油化工学院 |
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Abstract: |
The electrochemical behaviors and electrochemical quantitative determination of meloxicam(MLX) at acetylene black(AB) and 1-benzyl-3-methylimidazole hexafluorophosphate([BnMIM]PF6) ionic liquid composite modified carbon paste electrode(AB-[BnMIM]PF6/CPE) were investigated by electrochemical methods.The experimental results indicated that AB-[BnMIM]PF6/CPE showed a good promotion for MLX electrochemical oxidation.The electrode reaction kinetics parameters of MLX on AB-[BnMIM]PF6/CPE were measured.There are good linear relationships between oxidation peak current of MLX and its concentration in the ranges of 6.0×10-7-1.0×10-5 mol?L-1 and 1.0×10-5-1.0×10-4 mol?L-1.The linear equations are Ip(μA)=7.607+1 608 C(mmol?L-1),r=0.993 4,and Ip(μA)=20.68+267.6 C(mmol?L-1),r=0.997 9,respectively.The limit of detection(S/N=3) is 2.2×10-8 mol?L-1.The proposed method was successfully applied in the electrochemical quantitative determination of MLX contents in commercial tablet samples with RSDs of 1.2%-3.0% and recoveries of 96.2%-100.1%. |
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