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Detection of Ultra-trace Glucose Based on Au@Ag NRs as SERS Substrate |
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DOI: |
KeyWord:Au@Ag NRs surface enhanced Raman scattering(SERS) ultra-trace glucose Rhodamine 6G(R6G) |
Author | Institution |
FU Yu,ZHANG Wei-hong,GONG Li,WEN Jin-xiu,LIANG Zheng,GONG Yu-ting,XIE Fang yan,CHEN Jian* |
1.中山大学测试中心;2.中山大学化学与化学工程学院 |
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Abstract: |
In this work,Au NRs were synthesized by a two-step seed mediated growth method,and Au@Ag NRs were synthesized as SERS substrate through the chemical reduction method.The substrate was used to detect R6G as low as 10-18 mol/L.The Au@Ag NRs substrate has a good enhanced effect with enhanced factor of ca.1011.For the glucose deposited on the substrate with concentrations from 10-14 mol/L to 10-8 mol/L,the SERS signal intensity performs a linear change with logarithm concentrations of glucose.The experimental results showed that this method has a potential application prospect in ultra-trace glucose detection and semi-quantitative analysis. |
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