Determination of Carbofuran,Atrazine,Carbaryl and 6 Kinds of Phthalate Esters(PAEs) in Environmental Water by SPE-UPLC-MS/MS

KeyWord:carbofuran  atrazine  carbaryl  phthalate-esters(PAEs)  UPLC-MS/MS  environmental water

Abstract:

      An analytical method was developed for the simultaneous determination of carbofuran,atrazine,carbaryl and 6 kinds of phthalate esters(PAEs) in environmental water by ultra performance liquid chromatography coupled with tandem quadrupole mass spectrometry(UPLC-MS /MS).The samples were extracted and purified with Pak C18 solid extraction phase(SPE) cartridge.The targeted compounds were separated on BEH C18 column with methanol water solution as mobile phase ,determined under multiple reactions monitoring(MRM) mode and quantified by the external standard method.Under the optimized condition,the calibration curves were linear in the range of 0.5-20.0 ¦Ìg/L with correlation coefficients larger than 0.998.The limits of detection(LOD) and the limits of quantitation(LOQ) of the method were in the ranges of 0.05-0.12 ¦Ìg/L and 0.2-0.3 ¦Ìg/L,respectively.The recoveries were between 86.0% and 96.5%,with RSDs(n=6) less than 5%.This method was sensitive,accurate and reliable, and was suitable for the determination of carbofuran,atrazine,carbaryl and 6 kinds of phthalate esters(PAEs) in environmental water.