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Discovery and Structure Identification of a New Phosphodiesterase-5 Inhibitor Derivative |
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DOI: |
KeyWord:PDE-5 inhibitor analogue UPLC-QTOF-MS NMR IR structure identification |
Author | Institution |
MA Chun-yan,DUAN Qiong,FENG Shu-hua* |
河北省药品检验研究院 |
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Abstract: |
One suspected phosphodiesterase-5 inhibitor(PDE-5) derivative was found in a kind of medicinal liquor by UPLC-DAD-QTOF-MS.Sample purification was carried out by a preparative HPLC system,and its structure was determined by NMR,IR and UPLC-DAD-QTOF-MS methods.The results showed that the compound is a new aildenafil derivative which has never been reported at home and abroad. |
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