Extraction of Trace Microcystins in Water Using Fe3O4 @NiSiO3

KeyWord:magnetic solid-phase extraction£¨MSPE£©  high performance liquid chromatography£¨HPLC£©  microcystins£¨MCs£©  magnetic nanoparticles

Abstract:

      The Fe3O4@NiSiO3 magnetic nanoparticles£¨NPs£© were prepared by hydrothermal synthesis and sol-gel method.The nanoparticles microspheres have uniform morphology£¬good magnetic properties and dispersion.In this study£¬the synthesized NPs as a magnetic solid phase extraction£¨MSPE£© media were combined with high performence liquid chromatography£¨HPLC£© to develop an effective method for the detection of trace microcystin-LR£¨MC-LR£© in water samples.After optimizing the MSPE and HPLC chromatographic conditions£¬the method showed a good linear relationship in the range of 0.25-146.5 ¦Ìg/L with correlation coefficient£¨r£© of 0.999 1.The detection limit was 0.011 ¦Ìg/L.The method was applied in the analysis of microcystin toxins in pure water sample and actual water samples with recoveries of 81.0% and 66.7%-72.0%£¬respectively.The results showed that Fe3O4 @NiSiO3 magnetic nanoparticles have good enrichment capability£¬and could be effectively used for the extraction of trace microcystin in water.