Determination of Benzotriazole UV Stabilizers in Water Samples by Dispersive Liquid-Liquid Microextraction Combined with Gas Chromatography-Tandem Mass Spectrometry

KeyWord:benzotriazole UV stabilizers  dispersive liquid-liquid microextraction(DLLME)  gas chromatography-tandem mass spectrometry£¨GC-MS/MS£©  water

Abstract:

      A novel dispersive liquid-liquid microextraction method was developed for the determination of six kinds of benzotriazole UV stabilizers:UV-P,UV-PS,UV-326,UV-327,UV-328 and UV-329 in water samples by gas chromatography with tandem mass spectrometry£¨GC-MS/MS£©.The optimal liquid-liquid microextraction experiment conditions were as follows:50 ¦ÌL chloroform as extractant solvent£¬600 ¦ÌL ethanol as dispersive solvent£¬pH value of sample:3.0£®The target compounds were separated on a Rtx¡k-5MS column£¨30 m¡Á0.25 mm¡Á0.25 ¦Ìm£© and subsequently determined by triple quadruple mass spectrometry in multiple reaction monitoring mode.Quantitative determination was achieved by the external standard method.The average recoveries of target compounds were in the range of 83.5%-104.5%,with relative standard deviations£¨RSD,n=5£© of 5.1%-10.1%.The method detection limits£¨LOD£© for the six target compounds were in the range of 0.002-0.03 ¦Ìg/L and the quantitation limits£¨LOQ£© were 0.008-0.1 ¦Ìg/L.