Research Progress for Analytical Methods of Adenosine Deaminase Activity
  
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KeyWord:adenosine deaminase  activity analysis  clinical test  chromatography  adapter sensor
  
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XU Ran,QI Yan-fei,LI You-xin* 天津大学药物科学与技术学院,天津市现代药物传递及功能高效化重点实验室,天津化学化工协同创新中心
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Abstract:
      Adenosine deaminase(ADA), a kind of catabolic enzymes toward nucleic acid,has a close relationship with cell immunocompetence.ADA activity is abnormal in many diseases.Therefore,more and more researchers have been focusing on research of the relationship between ADA activity and some diseases.Analysis of the ADA activity is considered to has a very important significance in clinical diagnosis and treatment of diseases.Currently,many reports about novel analysis methods of ADA activity have been published,but no relevant reviews have been reported so far.In this paper,analytical methods of ADA activity such as colorimetric,chromatography and adapter sensor methods,are summarized,which is expected to provide references for the analysis of ADA.
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