Detection of 6-Hydroxynicotinic Acid in Nicotinic Acid Conversion Fluid Using Molecularly Imprinted Polymer Capped Mn-doped ZnS Phosphorescent Quantum Dots

KeyWord:quantum dots  molecular imprinting  phosphorescence detection  6-hydroxynicotinic acid£¨6-HNA£©  nicotinic acid

Abstract:

      An optical nanosensor based Mn doped ZnS quantum dots£¨QDs£©was synthesized using 6-hydroxynictinic acid£¨6-HNA£© as template via surface molecular imprinting sol-gel method.Fourier transform infrared spectroscopic£¨FT-IR£© spectra and scanning electron microscopic£¨SEM£© images showed that the imprinted polymer was successfully grafted onto MIP-QDs.Adsorption tests revealed that the affinity and selectivity of MIP-QDs for 6-HNA were significantly higher than its analogues nicotinic acid and coumalic acid.Under the optimized conditions,a phosphorescent sensor for detecting 6-HNA was constructed.The linear range for detection of 6-HNA was in the range of 3.4-67.0 ¦Ìmol/L with a detection limit of 1.03 ¦Ìmol/L and a correlation coefficient£¨r2£© of 0.996 5.Recoveries of 91.0%-103.9% and relative standard deviations less than 4.5% were achieved in real samples,which were in good agreement with that of the high performance liquid chromatographic£¨HPLC£© method£¨P>0.05£©.The proposed method had good veracity and feasibility.