| Photodynamic therapy（PDT）has emerged as one of the important therapeutic options for cancers.However,traditional photosensitizers have some defects such as poor selectivity and low photo-stability,which limit their clinical applications.Fortunately,some fluorescence molecules with aggregation-induced emission（AIEgens）characteristics could be used as a novel photosensitizer.The utilization of AIEgens has recently been developed at a tremendous pace,as compared with other materials,AIEgens possess various distinct advantages such as good biocompatibility,excellent fluorescent properties,simple preparation and modification,perfect size of nanoparticles for enhanced permeability and retention effect,etc.The advantages of AIEgens in PDT are introduced in this review,and the originative studies in PDT based on AIEgens in recent five years are systematically summarized.AIEgens would be a promising multifunctional material in PDT,and facilitate significant advancements in field of cancer therapy. |