|
Research Advances of Enrichment Approaches in N glycoproteomics |
|
View Full Text Download reader |
DOI: |
KeyWord:glycoproteomics N glycosylation glycopeptides glycoproteins enrichment |
Author | Institution |
SHAO Wen ya,LIANG Yu,LIANG Zhen,ZHANG Li hua,ZHANG Yu kui |
1.中国科学院大连化学物理研究所中国科学院分离分析化学重点实验室;2.中国科学院大学 |
|
Hits: 1974 |
Download times: 805 |
Abstract: |
Protein glycosylation is one of the most important post translational modifications.However,the great challenges for glycosylation of protein/peptides are the inherently low abundance and the poor ionization efficiency in mass spectrometry identification.Therefore,the specific enrichment before MS identification is indispensable.The basic principles,characteristics and recent progresses of the enrichment approaches for glycosylated proteins/peptides are reviewed,and the development prospects of the enrichment approaches for N glycosylated proteins/peptides are also outlined. |
Close |
|
|
|