Liquid Chromatography-Mass Spectrometry Analysis on the Chemical Weapon Related Compounds in the Aqueous Decontamination Effluent of the 42nd Official OPCW Proficiency Test

KeyWord:liquid chromatography-mass spectrometry£¨LC-MS£©  chemical weapon related compounds  aqueous decontamination effluent

Abstract:

      A method of liquid chromatography mass spectrometry£¨LC-MS£© was used to analyze the chemical weapon related compounds in the aqueous decontamination effluent samples of the 42nd Official Organization for the Prohibition Chemical Weapons£¨OPCW£© Proficiency Test.Firstly£¬the blank sample£¬control sample and simulated sample were distinguished by HPLC-Q-TOF MS from the three aqueous decontamination effluent samples£¬then three chemical weapon related compounds were preliminarily found out in simulated sample.Finally£¬2-hydroxyethyl vinyl sulfide£¬divinyl sulfone and 1,2-bis£¨2-hydroxyethylthio£©ethane in the simulated sample were identified simultaneously by UPLC-QQQ MS.The buffer agents£¬fragmentor voltages and fragmentation pathway were discussed adequately.The results obtained were in accordance with the list of spiking chemicals provided by the laboratory of OPCW.The method could provide a reference for the analysis on the decontamination products of sulfur mustard.