Determination of 20 Phthalates in Consumer Products by Two-dimensional Gas Chromatography-Time-of-flight Mass Spectrometry

KeyWord:two dimensional gas chromatography tandem with time of flight mass spectrometry  phthalates  dispersive solid phase extraction  consumer products

Abstract:

      An analytical method was developed for screening and quantitative detection of 20 phthalates (PAEs) in consumer products by two-dimensional gas chromatography-time of flight mass spectrometry(GC¡ÁGC-TOF MS).Samples were shattered,and followed by ultrasonic extraction with hexane.The extract was purified by dispersive solid phase extraction(dSPE) with graphitized carbon black(GCB) and magnesium sulfate anhydrous(MgSO4),analyzed by time-of-flight mass spectrometry and quantified by external standard method.Experimental results demonstrated that there were good linear relationships for 20 PAEs in the range of 0.03-30 mg/L with their correlation coefficients(r2) larger than 0ª±99.The limits of detection(LODs) and limits of quantitation(LOQs) were in the ranges of 0.09-22ª±13 mg/kg and 0.25-63.1 mg/kg,respectively.The recoveries at low,medium and high three spiked levels ranged from 63.2% to 120% with relative standard deviations(RSDs,n=6) of 0.30%-10%.This method was practically used in the detection for different samples.Results showed that diisononyl phthalate was found containing 1ª±55 mg/kg in a plastic sample,and dibutyl phthalate and di(2-ethylhexyl) phthalate were 1.48 mg/kg and 7.66 mg/kg in a rubber sample,respectively.This method could be applied in the determination of 20 phthalates including 5 phthalate isomers in consumer products with accuracy,efficiency and easy pretreatment.