Determination of Migration of 2-Methyl-1£¬3-Propanediol and 2£¬2- Methyl-1£¬3-Propanediol in Food Contact Materials by Gas Chromatography£­Mass Spectrometry

KeyWord:2-methyl-1,3-propanediol£¨MPO£©  2,2-methyl-1,3-propanediol£¨NPG£©  food contact materials  gas chromatography£­mass spectrometry £¨GC£­MS£©  derivatization method

Abstract:

      A gas chromatography£­mass spectrometry£¨GC£­MS£© was developed for the determination of migration of 2-methyl-1£¬3-propanediol£¨MPO£© and 2£¬2-methyl-1£¬3-propanediol£¨NPG£©in food contact materials. After the migration test of food contact materials£¬the obtained soaking solution was firstly derivatized with phenylboric acid solution£¬then extracted with n-hexane£¬and finally determined by GC£­MS. Results showed that there were good linear relationship of this method in the optimized conditions£¬with correlation coefficients£¨r2£© larger than 0.995. The detection limits for MPO and NPG in 4% acetic acid£¬10% ethanol£¬50% ethanol and isooctane were all 0.01 mg/L within linear ranges of 0.02£­0.10 mg/L.The detection limit of MPO in 95% ethanol was 0.30 mg/L within a linear range of 0.50£­1.6 mg/L. The detection limit for NPG in 95% ethanol was 0.03 mg/L within a linear range of 0.05£­0.16 mg/L.The relative standard deviations£¨RSD£© of this method were in the range of 0.60%£­9.5%£¬and the average recoveries were 85.0%£­112%.With the high accuracy and sensitivity£¬the method could be used to determine the migration of 2-methyl-1£¬3-propanediol and 2£¬2-methyl-1£¬3-propanediol in food contact coatings and plastic products£¬ so as to meet the limited requirements of Chinese regulations.