Determination of 19 Antiseptic and Antifungal Agents Residues in Wooden Chopping Boards by Gas Chromatography£­Tandem Mass Spectrometry with Surface Sampling Method

KeyWord:wooden chopping board  ?sampling in surface  ?antiseptic and antifungal agent  ?gas chromatography£­tandem mass spectrometry£¨GC£­MS/MS£©  ?risk early warning

Abstract:

      A gas chromatography£­tandem mass spectrometry£¨GC£­MS/MS£© with surface sampling method was established for the determination of 19 kinds of antiseptic and antifungal agents residues in wooden chopping boards£®The samples were prepared by surface sampling method£¬followed by acidification£¬and then extracted with ethyl acetate£­n-hexane£¨2¡Ã8£¬volume ratio£© mixed solvent£®The optimized method eliminated the need for derivatization reactions and purification operations£®Multi-reaction monitoring scanning mode£¨MRM£© was used for monitoring£¬and the external standard method with matrix-matched solution was used for quantification£®Results of the optimized analysis showed that there were good linear relationships for the 19 components in the range of 0.005£­200.0 ¦Ìg/mL£¬with their correlation coefficients£¨r2£© larger than 0.990£®The limits of detection£¨LODs£¬S/N?= 3£© and limits of quantitation£¨LOQs£¬S/N?= 10£© were in the ranges of 0.001£­0.17 mg/kg and 0.003£­0.55 mg/kg£¬respectively£®The recoveries for the 19 targets at two spiked concentration levels ranged from 65.8% to 97.2%£¬with relative standard deviations£¨RSDs£¬n?= 6£© of 4.3%£­13%£®This method was used for special food safety risk monitoring on the bamboo and wooden products related to food in Guizhou province£¬and the hidden risks of high pentachlorophenol residues in non-shaped packaging wooden chopping boards were discovered£¬which could provide an early risk warning for relevant departments£®