Investigation on Degradation of Dicofol in Gas Chromatography System

KeyWord:dicofol  degradation  the temperature of the inlet  solvent  quantification  gas chromatography system

Abstract:

      Gas chromatography system was utilized to identify the main degradation products and structures of dicofol£®Its degradation behaviors in the inlet and organic solvents were investigatied and the measures to minimize the degradation effects on the analysis were proposed£®The results showed that the main degradation products of dicofol£¬in addition to the reported 4£¬4'-DBP£¬were obtained through the de-chlorination pathway£®Generally£¬dicofol is stable when the inlet temperature is lower than 260 ¡æ£¬and it is stable in toluene but completely degrade to 4£¬4'-DBP in acetone and acetonitrile£®Meanwhule£¬anhydrous solvent could slow down the degradation process£®In ethyl acetate£¬dicofol could be partly degraded by dechlorination£®The addition of halides to the solvent could prohibit the dechlorination£®Dicofol£¬4£¬4'-DBP and degraded products were used to determine the residual amount of dicofol in the actual sample matrix by measuring the sum of the three peak areas due to the uncertainty of the sample matrix polarity£®The average recoveries of this method for three matrixes at 0.01£¬0.05 and 0.1 mg/kg spiked levels ranged from 72.5% to 110%£¬with the relative standard deviations£¨RSDs£¬n = 6£© of 5.1%£­10%£®This study provides an experimental basis for accurate£¬qualitative and quantitative detection of dicofol£¬which is of a certain reference value for exploring the degradation of compounds with the smilar structure.