Progresses in Magnetic Lateral Flow Assay for Rapid Detection of Food Contaminants
  
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KeyWord:magnetic lateral flow assay  food safety  rapid detection techniques  magnetic nanomaterials  immuno-chromatography assay  foodborne pathogens  mycotoxins  veterinary drug residues
  
AuthorInstitution
ZHAI Wen-lei,HAN Chen-rui,WEI Di-zhe,XIAO Zhi-yong,KONG Cong,WANG Meng 1. Institute of Quality Standard and Testing Technology,Beijing Academy of Agriculture and Forestry Sciences,Beijing ,China; 2. Beijing Center of AGRI-Products Quality and Safety,Beijing ,China; 3. East China Sea Fisheries Research Institute,Chinese Academy of Fishery Sciences,Shanghai ,China; 4. College of Food Science and Nutritional Engineering,China Agricultural University,Beijing ,China
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Abstract:
      Magnetic lateral flow assay(MLFA) is a rapid detection technique using magnetic nanomaterials as functional materials and lateral flow test strips as the analytical platform.It preserves many advantages of traditional lateral flow assay,such as easy operation,fast and real time analysis and low cost.Moreover,the sensitivity and accuracy of lateral flow assay could be further improved by combining with functionalized magnetic nanomaterials,mainly due to the capability of magnetically separating and enriching target analytes from complex matrixes.As a result,MLFA exhibits good performance and great potentials in rapid detection of many fields including food quality and safety.The development of MLFA for food safety in the last five years is mainly emphasized in this review.Different types of magnetic nanomaterials and the principles of MLFA are introduced.Based on various targets,the recent progresses in MLFA detection of foodborne bacteria and hazardous small molecules such as mycotoxins and veterinary drugs are summarized,respectively.In the end,the current stage and future development of MLFA technique are also discussed.
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