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| Research and Application of Carbon Fiber Ionization Mass Spectrometry |
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| DOI： |
| KeyWord:ambient ionization mass spectrometry（AIMS） carbon fiber ionization mass spectrometry principle of carbon fiber ionization mass spectrometry effecting factors application |
| Author | Institution |
| KONG Ran，XIANG Ping，CHEN Zhuo-nan，ZHAO Jun-bo |
1. Shanghai Key Laboratory of Forensic Medicine，Shanghai Forensic Service Platform，Department of Forensic Toxicology，Shanghai ，China; 2. School of Pharmacy，Yantai University，Yantai ，China |
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| Abstract: |
| Carbon fiber ionization technology is a new kind of ambient ionization mass spectrometry technology，which could be used for detection on various forms of samples or sample surface material in open environment．This technology could simplify the work flow，reduce the matrix effect of samples and expand its application with the advantages of low cost，high throughput，simplicity，real time and rapidness．The main factors affecting the ionization efficiency，such as carbon fiber shape，carbon fiber temperature，voltage applied to carbon fiber，distance between carbon fiber and ion injection port，and sample adding method are introduced in this paper，based on the principle of carbon fiber ionization mass spectrometry technology．Furthermore，the improvement and development of the technology in recent years，and its application in the food and drug safety，forensic toxicology test，species identification and biological samples and environmental analysis are summarized，and the applications of the characteristics and advantages of this technology are introduced in detail．Finally，the existing shortcomings and future research directions of carbon fiber ionization mass spectrometry are discussed. |
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